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Jul-27-2011 19:45printcommentsVideo

DNA Expert on the Amanda Knox Case

This fascinating case will likely be over early this fall.

Amanda Knox
Amanda Knox photo courtesy:

(ROME) - The Independent DNA Experts review of the Kitchen Knife and the Bra Clasp evidence has been turned in and the first court date discussing the results was on July 25.  Dr. Greg Hampikian is a DNA expert who co-authored an Open Letter on 19 Nov 2009 along with Dr. Elizabeth Johnson and 7 others.  The Conti-Vecchiotti DNA review report’s findings are very much in line with the Open Letter.  The independent experts found the forensics flawed because international protocols were not followed, contamination and erroneous interpretation.

Dr. Hampikian is also the founder of the Idaho Innocence Project and an advisor for the defense.  He will be able to explain the findings in the report better than any other.  He has a cordial, humorous and accessible way of explaining forensics to non-scientists. 


Below are links to the DNA Exports Report and Dr. Hampikian’s views:


The Conti-Vecchiotti DNA experts review report: Conclusions


Dr Greg Hampikian - New Hope for Amanda Knox


Dr. Greg Hampikian on the Knox-Sollecito case


DNA Experts Open Letter – 19 Nov 2009



This fascinating case will likely be over early this fall.  Now is the best time to bring it to the public.  If you are interested in interviewing Dr. Greg Hampikian please contact him at:



Conclusions (2)

Based on the considerations explained above, we are able to respond as follows to the inquiries posed at the assignment hearing:

“Having examined the record and conducted such technical investigations as shall be necessary, the Expert Panel shall ascertain:

1. whether it is possible, by means of a new technical analysis, to identify the DNA present on items 165b (bra clasp) and 36 (knife), and to determine the reliability of any such identification“

- The tests that we conducted to determine the presence of blood on item 36 (knife) and item 165B (bra clasps) yielded a negative result.

- The cytomorphological tests on the items did not reveal the presence of cellular material. Some samples of item 36 (knife), in particular sample “H”, present granules with a circular/hexagonal characteristic morphology with a cental radial structure. A more detailed microscopic study, together with the consultation of data in the literature, allowed us to ascertain that the structures in question are attributable to granules of starch, thus matter of a vegetable nature.

- The quantification of the extracts obtained from the samples obtained from item 36 (knife) and item 165B (bra clasps), conducted via Real Time PCR, did not reveal the presence of DNA.

- In view of the absence of DNA in the extracts that we obtained, with the agreement of the consultants for the parties, we did not proceed to the subsequent amplification step.

2. “if it is not possible to carry out a new technical analysis, shall evaluate, on the basis of the record, the degree of reliability of the genetic analysis performed by the Scientific Police on the aforementioned items, including with respect to possible contamination.“

Having examined the record and the relevant documents, we are able to report the following conclusions regarding the laboratory analyses performed on Item 36 (knife) and Item 165B (bra clasps):


Relative to the genetic analysis performed on trace A (handle of the knife), we agree with the conclusion reached by the Technical Consultant regarding the attribution of the genetic profile obtained from these samples to Amanda Marie Knox.

Relative to trace B (blade of the knife) we find that the technical analyses performed are not reliable for the following reasons:

1. There does not exist evidence which scientifically confirms that trace B (blade of knife) is the product of blood.

2. The electrophoretic profiles exhibited reveal that the sample indicated by the letter B (blade of knife) was a Low Copy Number (LCN) sample, and, as such, all of the precautions indicated by the international scientific community should have been applied.

3. Taking into account that none of the recommendations of the international scientific community relative to the treatment of Low Copy Number (LCN) samples were followed, we do not accept the conclusions regarding the certain attribution of the profile found on trace B (blade of knife) to the victim Meredith Susanna Cara Kercher, since the genetic profile, as obtained, appears unreliable insofar as it is not supported by scientifically validated analysis;

4. International protocols of inspection, collection, and sampling were not followed;

5. It cannot be ruled out that the result obtained from sample B (blade of knife) derives from contamination in some phase of the collection and/or handling and/or analyses performed.


Relative to Item 165B (bra clasps), we find that the technical analysis is not reliable for the following reasons:

1. There does not exist evidence which scientifically confirms the presence of supposed flaking cells on the item;

2. There was an erroneous interpretation of the electrophoretic profile of the autosomic STRs;

3. There was an erroneous interpretation of the electrophoretic profile relative to the Y chromosome;

4. The international protocols for inspection, collection, and sampling of the item were not followed;

5. It cannot be ruled out that the results obtained derive from environmental contamination and/or contamination in some phase of the collection and/or handling of the item.


Prof. Carla Vecchiotti

Prof. Stefano Conti

Comments Leave a comment on this story.

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RaSuMa312 July 29, 2011 7:25 pm (Pacific time)

Thanks for this excellent information. I do understand how the contamination, the mis-read low copy DNA has ruined these poor kids' lives. Trump is right: they should be freed NOW

Anonymous July 28, 2011 7:35 pm (Pacific time)

No, the consultant is not going to tell you the DNA was changed from one person to another.. they will confirm and tell you the only thing on that knife this whole time was starch... from rye bread...... soit was confirmed within more then reasonable doubt the only thing the knife stabbed was a loaf of bread. Pathetic.... the prosecutor and all those bimbos wasted and tried to ruin these kids life. SHAME!!!!!!!!!!!!!!!!!!!!!

ajax July 28, 2011 7:28 pm (Pacific time)

Of course contamination changes DNA from one person to another's -- from a viable suspect's to somebody whose DNA just happened to be where it could be transferred to the object in question. That is what contamination is! If I shake someone's hand, then pick up a kitchen knife, I will transfer that person's DNA to the knife. If the knife happened to have been recently used in a murder, are you suggesting we should arrest, convict and imprison the person whose hand I shook?

RickB July 28, 2011 7:06 pm (Pacific time)

Tomas, you should read more of Dr Hampikian's articles. He will explain how contamination can do just that... in layman's terms

Tomas July 28, 2011 11:07 am (Pacific time)

So once again, the consultant is going to tell us that contamination changed the DNA from one person into another's. Since that is not chemically possible, it is a lie.

GreyFox July 28, 2011 9:37 am (Pacific time)

Hopefuly the judge in this case can save a little face for the Italian system and let these kids go. Next step is to lock up this Mingini and throw away the key for all of the lies he's told!!

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